Tuesday, 22 February 2011

DNA Decoded…..Bring Better Health Home Through DNA Based Nutritional Supplements

From times immemorial, mankind has been plagued with to which they are unwillingly predisposed - aging, heart diseases, lung disorders, and immune system dysfunctions. And, for as many years scientists and researchers have toiled to have a better understanding on how a person’s body responds to various factors like environmental stresses. Although to some extent we were able to ward off certain life threatening diseases, still factors like aging and immune system dysfunctions were beyond comprehension. Well, here we are talking about pre-Human Genome Project era. After the completion of Human Genome Project in 2003, the future of wellness has become a reality. The completion of the Genomics Project gives us a whole new level of tools and understanding.

Genomic Scientists came up with a startling fact that after the mapping of DNA, your health and medical conditions can be analyzed. DNA mapping of a person can predict his predisposition towards the diseases and also how and why are his genes responding to the environmental pressures in a certain manner. In short, an individual’s susceptibility towards certain diseases depends on the genetic makeup. Stronger the genes, lesser would be the vulnerability towards diseases and weaker the genes, greater would be susceptibility towards the diseases.

Once the DNA mapping is done, nutritional supplements based on DNA are formulated that can promote the person’s health and wellness. DNA based nutritional supplements are proving to be a catalyst in the field of science as Genome scientists have discovered that due to impaired DNA and genetic code, a person can have diminished state of health; consequently, if supplements be made especially to repair the faulty genetic structure of an individual, then one can achieve the maximum health benefits. These nutritional supplements are a unique blend of whole food, organics, super fruit, plant based nutrition supplements that are scientifically proven to make a difference in health and wellness. DNA customized nutritional supplements are a perfect way to compensate for your particular deficiencies through your very own DNA and are undoubtedly better than taking harmful chemicals, possibly leading to a bunch of side-effects.

Wednesday, 2 February 2011

DNA Analysis

DNA, deoxyribonucleic acid, is known to be responsible for storing information of individual genetic traits. But lot of other information can also be attained by studying DNA such as an individual’s parentage, disease predisposition, etc. DNA is also responsible for a person's hair color, eye color, build, metabolism rate, susceptibility to certain disorders, and a lot more.

Human Genome Project which ended in 2003 revealed that careful scrutiny of the DNA can possibly help in establishing the fact about an individual’s susceptibility towards diseases. According to this finding every individual has unique genetically influenced body chemistry and our health is much influenced by these genes. Genome Scientists claim that an individual’s complete health being depends on his or her genetic code. Up till now DNA was only regarded as an important tool in medical and criminal investigations but after the Human Genome Project in 2003, scientists came up with a startling finding. High quality genes reduce the chances of one’s acquiring diseases and poor quality genes raise a person’s chance of acquiring diseases.

Thus, scientists have come up with a vital solution to control one’s susceptibility towards illness, and scientists along with pharmaceutical companies have created DNA tested supplements which enhance an individual’s health. These supplements are made to complement a person’s genetic structure and also to provide the essential nutrients to the body.

DNA customized supplements are made to repair the damaged genes as these supplements contain essential nutrients which help to regain the lost health and also to slow down the aging process. As these DNA tested supplements are tailor made, therefore, each supplement is based on an individual’s own requirements, augmenting the complete well being.

Tuesday, 4 January 2011

DNA Customized Nutrition….Correcting The Blueprints of Life

Great things were expected from Human Genome Project and truly, after the completion of the project in 2003, great things were revealed. Obviously, there were many findings during the project that startled the scientists and world but among the many discoveries, the most promising one were the diagnostic testing for the DNA that predispose to diseases, pharmacological applications such as targeted drug therapy, drug design and most importantly, the customized nutrition therapy. Yes, you are reading it right. DNA testing is no more restricted to tracing of the ancestors; rather DNA testing can reveal many locked doors of potential threats.

Our DNA holds the secret to how our body responds to various environmental pressures. DNA testing can expose the faulty genes present in the DNA that prove as a gateway to chronic diseases as well as to the hastened aging process. It is also possible through DNA testing to predict the probability that an individual will develop certain diseases. DNA testing measures single nucleotide polymorphism also called SNP in DNA. This assessment demonstrates which health areas of the individual have shortcomings. Even a small discrepancy in the genetic coding can cause our bodily functions and metabolism to slow down, ultimately prompting a fast aging process.

After determining any discrepancy in the DNA, DNA customized nutrition is prepared to prevent or delay the chronic diseases for which one’s genes may be at a risk. DNA customized nutrition contains the essential nutrients and other ingredients that are scientifically created to increase an individual’s ability to support his or her DNA.

Doesn’t it sound wonderful…that by a simple DNA testing, DNA customized nutrition is formulated, just for your body! So, it is high time that we say adieu to all our health problems.

Friday, 10 December 2010

Anti Aging Products Based On DNA

According to recent statistics, many young Americans flock to their doctor in search of various ways to wipe away life’s early signs of aging. Even modern science and technology are challenging the truth that life is finite and old age is inevitable. Scientists are burning the midnight oil in formulating some sort anti aging products that can deliver early detection, prevention, treatment and reversal of aging. They are constantly working to enhance the quality of human life span and this is what appears to be the most important riddle for this millennium.

Though not refuting the preeminence of modern science, let us also not forget that no matter what, one cannot escape the wrath of time. Andrew Marvell, the famous English poet has rhetorically stressed on time’s rage on a beauty in his poem, “To His Coy Mistress”: “Time's winged chariot hurrying near; and yonder all before us lie Deserts of vast eternity. Thy beauty shall no more be found”.

It is said that as soon as an individual takes birth, his or her process of dying starts. From the moment of birth, we begin a process of growth and development that continues in to the years of reproduction. However, as the Mother Nature dictates, most of us begin to experience lose muscle tone, and most importantly, the graceful motions of youth. Although admittedly, one cannot stop time or reverse back the aging clock but the only step to maintain the youthful appearance is to slow down the aging process.

During the Human Genome Project, scientists revealed that our DNA influences one’s ageing process. If an individual’s DNA is impaired or there is some flaw, then evidently, it starts showing up on the face and also it results in hastened aging process. Thus, to slow down this accelerated aging process, Anti aging products based on one’s DNA, are being prepared by many pharmaceutical companies. The idea behind these DNA based anti aging products is very simple: a DNA cheek swab test ascertains which faulty genes in the DNA are causing accelerated aging process. After this detection, DNA based Anti aging products is prepared to repair the damaged DNA or faulty genes. Anti aging products contain the essential nutrients that repair the damage done to the DNA by environmental stresses, thus, fighting the hastened aging process.

Monday, 9 August 2010

DNA Screenings: A Thing of the Future is hereDNA Screenings

Knowing your family's genetic history may someday save your life or that of someone you love. Based on genetic technology, a unique DNA analysis can be made for an individual, stating all the deficiencies and potential genetic disorders, thus, preparing one to fight the signs and symptoms of diseases. What better gift can a loved one leave behind?

The vast spectrum of DNA can give us insight on the value it can play in our lives. These startling revelations came into light during Human Genome Project. DNA research and Human Genome Mapping has allowed scientists to discover about how one’s unique DNA influences one’s health. Based on these studies, a simple DNA test at home lets a person know what exact supplements one’s body needs and how much. This revolutionary breakthrough has lead to the designing of vitamin supplements based on one’s unique DNA.

An individual’s DNA holds the secret to enhanced state of wellbeing as well as diminished state of wellbeing. Even a slight difference in this genetic code leads to a living being’s vulnerability to diseases. vitamin supplements are made after DNA analysis, meeting an individual’s needs and requirements to keep him or her healthy. Total wellbeing can be attained through DNA customized supplements as they contain the essential nutrients which help to regain the lost health and also slows the aging process. As these supplements are tailor made, therefore, each supplement is based on an individual’s own requirements, augmenting the complete well being

Sunday, 8 August 2010

QuikChIP Chromatin Immunoprecipitation Kits

IMGENEX QuikChIP Certified Antibodies The Basics...
The principle of the ChIP assay is simple: selective enrichment of a chromatin fraction containing a specific target. However, the process can be technically challenging. It is with these challenges in mind that IMGENEX developed the QuikChIP Kit for chromatin immunoprecipitation. QuikChIP includes optimized ready-to-use buffers and inhibitory reagents, as well as a comprehensive technical manual.

* Quick & simple
* Optimized ready-to-use buffers & protocol
* Useful for Histone and non-histone proteins

Reagents for 25 ChIP assays and sheared Chromatin preparations


QuikChIP Certified Antibodies

IMGENEX offers a growing number of antibodies that have been validated for use in ChIP assays and we are continually testing and validating new products for use in ChIP. Below is a list of our currently available QuikChIP Certified Antibodies. Be sure to check our website often as we are releasing new antibodies every week!

Sheared Chromatin

IMGENEX QuikChIP™ Sheared Chromatin is ready-to-use, sheared, cross-linked chromatin prepared from mammalian cell extracts. This novel product enables researchers to carry out ChIP assays in the absence of cell culture facilities or sonication equipment. It is also useful as a sheared, cross-linked chromatin positive control, alongside your own cell extracts.

Conditions for cell culture, DNA-protein cross-linking, and the sonication shearing process have been optimized for each human and mouse cell type.

IMGENEX has now p73 phosphospecific antibody

The p53 family member, p73, also known as tumor protein 73 (TP73) has been recently identified as a structural and functional homolog of the tumor suppressor protein p53. In accordance with its structural similarity, p73 functions in a manner analogous to p53 by inducing tumor cell apoptosis and participating in the cell cycle checkpoint control through transactivating an overlapping set of p53/p73-target genes. Under these conditions p73 is tyrosine-phosphorylated by c-Abl, a prerequisite modification for p73 to elicit cell death in fibroblasts. Increasing knowledge of its function, however, has cast doubts on its role. Like p53, the protein contains different isoforms with distinct and sometimes opposite functions.
Like other members of the p53 family, p73 protein share the same modular organization consisting of an N-terminal transactivation domain, central sequence-specific DNA-binding domain, and a C-terminal tetramerization domain. However, the p73 gene encodes multiple isoforms varying in their N and C termini. In some cases, the use of a cryptic promoter generates isoforms lacking the transactivation domain located in the N terminus of p73 (deltaNp73 alpha and deltaNp73 beta). The p73 gene also generates several forms with varying C-terminal extensions,TAp73 (p73 alpha, beta, gamma, delta and epsilon). These splicing variants are expressed differently in normal human tissues and cell lines. The p73 gene has been mapped to human chromosome 1p36, a region that is frequently deleted in variety of human cancers including neuroblastoma, colon cancer, and breast cancer.
The precise functions of p73 proteins in the organism and the signaling pathways that regulate their activity are still not well established. An interesting recent report shows that p73 is required for p53-dependent apoptosis induced by DNA damage as well as p53-independent apoptosis. These observations and the fact that p73 expression is affected in certain tumors suggest that p73 may function as a tumor suppressor gene. However, p73 deficient mice are not particularly prone to cancer, and only rarely have mutation or inactivation of p73 expression been found in human tumors. On the contrary the deltaNp73 isoforms have oncogenic potential and act in a dominant negative manner against TAp73 as well as p53. The Delta N isoforms of p73 can also protect neurons from apoptosis. Besides like p53, p73 may also play a role in developmental processes. Several lines of evidence show that p73 may play a role in nervous system and immune system development, thus implicating the role of p73 in cellular differentiation.